Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR)

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the biological and toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), dioxin-like compounds (DLC) as well as some drugs and endogenous tryptophan metabolites. Short-term activation of AhR can lead...

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Publicado en:Toxicology
Autores principales: Oshida, Keiyu, Vasani, Naresh, Thomas, Russell S., Applegate, Dawn, Gonzalez, Frank J., Aleksunes, Lauren M., Klaassen, Curtis D., Corton, J. Christopher
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661527/
https://ncbi.nlm.nih.gov/pubmed/26215100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2015.07.005
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