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Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

The nuclear receptor family member peroxisome proliferator-activated receptor α (PPARα) is activated by therapeutic hypolipidemic drugs and environmentally-relevant chemicals to regulate genes involved in lipid transport and catabolism. Chronic activation of PPARα in rodents increases liver cancer i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Oshida, Keiyu, Vasani, Naresh, Thomas, Russell S., Applegate, Dawn, Rosen, Mitch, Abbott, Barbara, Lau, Christopher, Guo, Grace, Aleksunes, Lauren M., Klaassen, Curtis, Corton, J. Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331523/
https://ncbi.nlm.nih.gov/pubmed/25689681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112655
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