Characterization of Peroxisome Proliferator–Activated Receptor α—Independent Effects of PPARα Activators in the Rodent Liver: Di-(2-ethylhexyl) phthalate also Activates the Constitutive-Activated Receptor

Peroxisome proliferator chemicals (PPC) are thought to mediate their effects in rodents on hepatocyte growth and liver cancer through the nuclear receptor peroxisome proliferator–activated receptor (PPAR) α. Recent studies indicate that the plasticizer di-(2-ethylhexyl) phthalate (DEHP) increased th...

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Hlavní autoři: Ren, Hongzu, Aleksunes, Lauren M., Wood, Carmen, Vallanat, Beena, George, Michael H., Klaassen, Curtis D., Corton, J. Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Carcinogenicity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794335/
https://ncbi.nlm.nih.gov/pubmed/19850644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp251
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