YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity

Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates glucose, lipid, and energy homeostasis. While gene expression of FGF21 is regulated by the nuclear hormone receptor peroxisome proliferator-activated receptor alpha in the fasted state, little is known about the regulation of...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Wang, Lirui, Mazagova, Magdalena, Pan, Chuyue, Yang, Song, Brandl, Katharina, Liu, Jun, Reilly, Shannon M., Wang, Yanhan, Miao, Zhaorui, Loomba, Rohit, Lu, Na, Guo, Qinglong, Liu, Jihua, Yu, Ruth T., Downes, Michael, Evans, Ronald M., Brenner, David A., Saltiel, Alan R., Beutler, Bruce, Schnabl, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660779/
https://ncbi.nlm.nih.gov/pubmed/31289229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904360116
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