YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity

Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates glucose, lipid, and energy homeostasis. While gene expression of FGF21 is regulated by the nuclear hormone receptor peroxisome proliferator-activated receptor alpha in the fasted state, little is known about the regulation of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Lirui, Mazagova, Magdalena, Pan, Chuyue, Yang, Song, Brandl, Katharina, Liu, Jun, Reilly, Shannon M., Wang, Yanhan, Miao, Zhaorui, Loomba, Rohit, Lu, Na, Guo, Qinglong, Liu, Jihua, Yu, Ruth T., Downes, Michael, Evans, Ronald M., Brenner, David A., Saltiel, Alan R., Beutler, Bruce, Schnabl, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660779/
https://ncbi.nlm.nih.gov/pubmed/31289229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904360116
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