Antibody-dependent enhancement of influenza disease promoted by increase in hemagglutinin stem flexibility and virus fusion kinetics

Several next-generation (universal) influenza vaccines and broadly neutralizing antibodies (bNAbs) are in clinical development. Some of these mediate inhibitions of virus replication at the postentry stage or use Fc-dependent mechanisms. Nonneutralizing antibodies have the potential to mediate enhan...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Winarski, Katie L., Tang, Juanjie, Klenow, Laura, Lee, Jeehyun, Coyle, Elizabeth M., Manischewitz, Jody, Turner, Hannah L., Takeda, Kazuyo, Ward, Andrew B., Golding, Hana, Khurana, Surender
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2019
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660725/
https://ncbi.nlm.nih.gov/pubmed/31296560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821317116
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