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Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model

In current study, we evaluated the safety and protective efficacy of recombinant unglycosylated RSV G protein ectodomain produced in E. coli (in presence and absence of oil-in-water adjuvant) in a preclinical RSV susceptible cotton rat challenge model compared to formaldehyde inactivated RSV (FI-RSV...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Fuentes, Sandra, Klenow, Laura, Golding, Hana, Khurana, Surender
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301242/
https://ncbi.nlm.nih.gov/pubmed/28186208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42428
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