Microfluidic protein isolation and sample preparation for high-resolution cryo-EM

High-resolution structural information is essential to understand protein function. Protein-structure determination needs a considerable amount of protein, which can be challenging to produce, often involving harsh and lengthy procedures. In contrast, the several thousand to a few million protein pa...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Schmidli, Claudio, Albiez, Stefan, Rima, Luca, Righetto, Ricardo, Mohammed, Inayatulla, Oliva, Paolo, Kovacik, Lubomir, Stahlberg, Henning, Braun, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660723/
https://ncbi.nlm.nih.gov/pubmed/31292253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907214116
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