Miniaturized Sample Preparation for Transmission Electron Microscopy

Due to recent technological progress, cryo-electron microscopy (cryo-EM) is rapidly becoming a standard method for the structural analysis of protein complexes to atomic resolution. However, protein isolation techniques and sample preparation methods for EM remain a bottleneck. A relatively small nu...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Schmidli, Claudio, Rima, Luca, Arnold, Stefan A., Stohler, Thomas, Syntychaki, Anastasia, Bieri, Andrej, Albiez, Stefan, Goldie, Kenneth N., Chami, Mohamed, Stahlberg, Henning, Braun, Thomas
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2018
Subjects:
Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126565/
https://ncbi.nlm.nih.gov/pubmed/30102271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57310
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