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Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM

Electron crystallography can reveal the structure of membrane proteins within 2D crystals under close-to-native conditions. High-resolution structural information can only be reached if crystals are perfectly flat and highly ordered. In practice, such crystals are difficult to obtain. Available imag...

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Foilsithe in:Nat Commun
Main Authors: Righetto, Ricardo D., Biyani, Nikhil, Kowal, Julia, Chami, Mohamed, Stahlberg, Henning
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461647/
https://ncbi.nlm.nih.gov/pubmed/30979902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09661-5
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