Valproic Acid Improves Survival and Decreases Resuscitation Requirements In a Swine Model of Prolonged Damage Control Resuscitation

BACKGROUND: Although damage control resuscitation (DCR) is routinely performed for short durations, prolonged DCR may be required in military conflicts as a component of prolonged field care. Valproic acid (VPA) has been shown to have beneficial properties in lethal hemorrhage/trauma models. We soug...

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Veröffentlicht in:J Trauma Acute Care Surg
Hauptverfasser: Williams, Aaron M., Bhatti, Umar F., Biesterveld, Ben E., Graham, Nathan J., Chtraklin, Kiril, Zhou, Jing, Dennahy, Isabel S., Kathawate, Ranganath G., Vercruysse, Claire A., Russo, Rachel M., Li, Yongqing, Alam, Hasan B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660397/
https://ncbi.nlm.nih.gov/pubmed/31206419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002281
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