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Hypoxic Regulation of Angiotensin-Converting Enzyme 2 and Mas Receptor in Human CD34(+) Cells

CD34(+) hematopoietic stem/progenitor cells (HSPCs) are vasculogenic and hypoxia is a strong stimulus for the vasoreparative functions of these cells. Angiotensin converting enzyme-2 (ACE2)/Angiotensin-(1-7)/Mas receptor (MasR) pathway stimulates vasoprotective functions of CD34(+) cells. This study...

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Publicat a:J Cell Physiol
Autors principals: Joshi, Shrinidh, Wollenzien, Hannah, Leclerc, Estelle, Jarajapu, Yagna PR
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660366/
https://ncbi.nlm.nih.gov/pubmed/30989646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.28643
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