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Hypoxic Regulation of Angiotensin-Converting Enzyme 2 and Mas Receptor in Human CD34(+) Cells

CD34(+) hematopoietic stem/progenitor cells (HSPCs) are vasculogenic and hypoxia is a strong stimulus for the vasoreparative functions of these cells. Angiotensin converting enzyme-2 (ACE2)/Angiotensin-(1-7)/Mas receptor (MasR) pathway stimulates vasoprotective functions of CD34(+) cells. This study...

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Detalles Bibliográficos
Publicado en:J Cell Physiol
Main Authors: Joshi, Shrinidh, Wollenzien, Hannah, Leclerc, Estelle, Jarajapu, Yagna PR
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660366/
https://ncbi.nlm.nih.gov/pubmed/30989646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.28643
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