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Angiotensin converting enzyme versus angiotensin converting enzyme-2 selectivity of MLN-4760 and DX600 in human and murine bone marrow-derived cells

Angiotensin-converting enzymes, ACE and ACE2, are key members of renin angiotensin system. Activation of ACE2/Ang-(1-7) pathway enhances cardiovascular protective functions of bone marrow-derived stem/progenitor cells. The current study evaluated the selectivity of ACE2 inhibitors, MLN-4760 and DX-6...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Joshi, Shrinidh, Balasubramanian, Narayanaganesh, Vasam, Goutham, Jarajapu, Yagna PR
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804635/
https://ncbi.nlm.nih.gov/pubmed/26851370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.01.007
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