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Design and characterisation of a novel interleukin-15 receptor alpha fusion protein and analysis of interleukin-15 complexation

Interleukin-15 (IL15) is one of the most important cytokines currently being considered for cancer therapy applications. It is thought that by administering IL15 in complex with its cognate receptor alpha chain (IL15Rα) its biological activity could be increased manifold. We produced a fusion protei...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schmid, Anja Sophie, Neri, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660064/
https://ncbi.nlm.nih.gov/pubmed/31348785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219313
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