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Contextualizing selection bias in Mendelian randomization: how bad is it likely to be?

BACKGROUND: Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor–outcome association. However, the relative importance of selection bias for Mendelian randomization comp...

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Bibliographic Details
Published in:Int J Epidemiol
Main Authors: Gkatzionis, Apostolos, Burgess, Stephen
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659463/
https://ncbi.nlm.nih.gov/pubmed/30325422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy202
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