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Multiple Copies of qnrA1 on an IncA/C(2) Plasmid Explain Enhanced Quinolone Resistance in an Escherichia coli Mutant
In a previous study, mutants with enhanced ciprofloxacin resistance (Cip(r)) were selected from Escherichia coli J53/pMG252 carrying qnrA1. Strain J53 Cip(r) 8-2 showed an increase in the copy number and transcription level of qnrA1. We sequenced the plasmids on Illumina and MinION platforms. Parent...
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| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6658789/ https://ncbi.nlm.nih.gov/pubmed/31160282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00718-19 |
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