Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC

Carbapenem-resistant Enterobacteriaceae (CRE) are resistant to most antibiotics, making CRE infections extremely difficult to treat with available agents. Klebsiella pneumoniae carbapenemases (KPC-2 and KPC-3) are predominant carbapenemases in CRE in the United States. Nacubactam is a bridged diazab...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Barnes, Melissa D., Taracila, Magdalena A., Good, Caryn E., Bajaksouzian, Saralee, Rojas, Laura J., van Duin, David, Kreiswirth, Barry N., Jacobs, Michael R., Haldimann, Andreas, Papp-Wallace, Krisztina M., Bonomo, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658744/
https://ncbi.nlm.nih.gov/pubmed/31182530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00432-19
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