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Metabolic constraints drive self-organization of specialized cell groups
How phenotypically distinct states in isogenic cell populations appear and stably co-exist remains unresolved. We find that within a mature, clonal yeast colony developing in low glucose, cells arrange into metabolically disparate cell groups. Using this system, we model and experimentally identify...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6658198/ https://ncbi.nlm.nih.gov/pubmed/31241462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46735 |
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