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Metabolic constraints drive self-organization of specialized cell groups

How phenotypically distinct states in isogenic cell populations appear and stably co-exist remains unresolved. We find that within a mature, clonal yeast colony developing in low glucose, cells arrange into metabolically disparate cell groups. Using this system, we model and experimentally identify...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Varahan, Sriram, Walvekar, Adhish, Sinha, Vaibhhav, Krishna, Sandeep, Laxman, Sunil
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658198/
https://ncbi.nlm.nih.gov/pubmed/31241462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46735
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