Caricamento...
Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase η
Oxaliplatin, together with cisplatin, is among the most important drugs used in cancer chemotherapy. Oxaliplatin, which contains a bulky diaminocyclohexane (DACH) moiety, kills cancer cells mainly by producing (DACH)Pt-GpG intrastrand cross-links that impede transcription. The Pt-GpG tolerance by tr...
Salvato in:
| Pubblicato in: | Biochem J |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6657808/ https://ncbi.nlm.nih.gov/pubmed/30709915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180848 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|