Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts

Biological membranes show lateral and transverse asymmetric lipid distribution. Cholesterol (Chol) localizes in both hemilayers, but in the external one it is mostly condensed in lipid-ordered microdomains (raft domains), together with saturated phosphatidyl lipids and sphingolipids (including sphin...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Fabiani, Camila, Antollini, Silvia S.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657435/
https://ncbi.nlm.nih.gov/pubmed/31379503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00309
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