Molecular Modulation of Human α7 Nicotinic Receptor by Amyloid-β Peptides

Amyloid β peptide (Aβ) is a key player in the development of Alzheimer’s disease (AD). It is the primary component of senile plaques in AD patients and is also found in soluble forms. Cholinergic activity mediated by α7 nicotinic receptors has been shown to be affected by Aβ soluble forms. To shed l...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Lasala, Matías, Fabiani, Camila, Corradi, Jeremías, Antollini, Silvia, Bouzat, Cecilia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376857/
https://ncbi.nlm.nih.gov/pubmed/30800059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00037
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