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Amyloid-beta Alzheimer targets — protein processing, lipid rafts, and amyloid-beta pores

Amyloid beta (Aβ), the hallmark of Alzheimer’s Disease (AD), now appears to be deleterious in its low number aggregate form as opposed to the macroscopic Aβ fibers historically seen postmortem. While Alzheimer targets, such as the tau protein, amyloid precursor protein (APP) processing, and immune s...

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Pubblicato in:Yale J Biol Med
Autori principali: Arbor, Sage C., LaFontaine, Mike, Cumbay, Medhane
Natura: Artigo
Lingua:Inglês
Pubblicazione: YJBM 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797837/
https://ncbi.nlm.nih.gov/pubmed/27505013
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