(p)ppGpp and CodY Promote Enterococcus faecalis Virulence in a Murine Model of Catheter-Associated Urinary Tract Infection

In Firmicutes, the nutrient-sensing regulators (p)ppGpp, the effector molecule of the stringent response, and CodY work in tandem to maintain bacterial fitness during infection. Here, we tested (p)ppGpp and codY mutant strains of Enterococcus faecalis in a catheter-associated urinary tract infection...

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Udgivet i:mSphere
Main Authors: Colomer-Winter, C., Flores-Mireles, A. L., Kundra, S., Hultgren, S. J., Lemos, J. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656871/
https://ncbi.nlm.nih.gov/pubmed/31341072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00392-19
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