Association of Metal Homeostasis and (p)ppGpp Regulation in the Pathophysiology of Enterococcus faecalis

In Enterococcus faecalis, the regulatory nucleotides pppGpp and ppGpp, collectively, (p)ppGpp, are required for growth in blood, survival within macrophages, and virulence. However, a clear understanding of how (p)ppGpp promotes virulence in E. faecalis and other bacterial pathogens is still lacking...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Colomer-Winter, C., Gaca, A. O., Lemos, J. A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478964/
https://ncbi.nlm.nih.gov/pubmed/28483855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00260-17
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