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Association of Metal Homeostasis and (p)ppGpp Regulation in the Pathophysiology of Enterococcus faecalis

In Enterococcus faecalis, the regulatory nucleotides pppGpp and ppGpp, collectively, (p)ppGpp, are required for growth in blood, survival within macrophages, and virulence. However, a clear understanding of how (p)ppGpp promotes virulence in E. faecalis and other bacterial pathogens is still lacking...

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Pubblicato in:Infect Immun
Autori principali: Colomer-Winter, C., Gaca, A. O., Lemos, J. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478964/
https://ncbi.nlm.nih.gov/pubmed/28483855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00260-17
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