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(p)ppGpp and CodY Promote Enterococcus faecalis Virulence in a Murine Model of Catheter-Associated Urinary Tract Infection

In Firmicutes, the nutrient-sensing regulators (p)ppGpp, the effector molecule of the stringent response, and CodY work in tandem to maintain bacterial fitness during infection. Here, we tested (p)ppGpp and codY mutant strains of Enterococcus faecalis in a catheter-associated urinary tract infection...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Colomer-Winter, C., Flores-Mireles, A. L., Kundra, S., Hultgren, S. J., Lemos, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656871/
https://ncbi.nlm.nih.gov/pubmed/31341072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00392-19
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