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Genetic diversity of cytochrome P450 1A2 with different metabolic activities in domestic cats

Knowledge of genetic polymorphisms of metabolizing enzymes of medical drugs and xenobiotics including cytochrome P450 (CYP) is very limited in cats. We investigated polymorphisms in CYP1A2, one of the major CYP isoforms in the feline liver. Wild-type and three non-synonymous polymorphic variants, bu...

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Detalhes bibliográficos
Publicado no:J Vet Med Sci
Main Authors: SUGIYAMA, Souta, UNO, Yasuhiro, AMANO, Tomoko, KITAZAWA, Takio, TERAOKA, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Veterinary Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656809/
https://ncbi.nlm.nih.gov/pubmed/31118351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.19-0106
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