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Genetic diversity of cytochrome P450 3A with different metabolic activity in domestic cats

Knowledge on genetic polymorphisms of metabolising enzymes including cytochrome P450 (CYP) is very limited in cats. We investigated polymorphisms in CYP3A131, one of the major CYP isoforms in the feline liver and small intestine. Eight non-synonymous variants and one synonymous variant of feline CYP...

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Detalhes bibliográficos
Publicado no:J Vet Med Sci
Main Authors: SUGIYAMA, Souta, UNO, Yasuhiro, AMANO, Tomoko, KITAZAWA, Takio, TERAOKA, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Veterinary Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483910/
https://ncbi.nlm.nih.gov/pubmed/30828039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.18-0692
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