The MyoRobot technology discloses a premature biomechanical decay of skeletal muscle fiber bundles derived from R349P desminopathy mice

Mutations in the Des gene coding for the muscle-specific intermediate filament protein desmin lead to myopathies and cardiomyopathies. We previously generated a R349P desmin knock-in mouse strain as a patient-mimicking model for the corresponding most frequent human desmin mutation R350P. Since noth...

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Publicat a:Sci Rep
Autors principals: Haug, Michael, Meyer, Charlotte, Reischl, Barbara, Prölß, Gerhard, Vetter, Kristina, Iberl, Julian, Nübler, Stefanie, Schürmann, Sebastian, Rupitsch, Stefan J., Heckel, Michael, Pöschel, Thorsten, Winter, Lilli, Herrmann, Harald, Clemen, Christoph S., Schröder, Rolf, Friedrich, Oliver
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656739/
https://ncbi.nlm.nih.gov/pubmed/31341183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46723-6
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