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Endothelial Mineralocorticoid Receptors Contribute to Vascular Inflammation in Atherosclerosis in a Sex-Specific Manner

OBJECTIVE: Mineralocorticoid receptor (MR) activation is associated with cardiovascular ischemia in humans. This study explores the role of the MR in atherosclerotic mice of both sexes and identifies a sex-specific role for endothelial cell (EC)-MR in vascular inflammation. APPROACH AND RESULTS: In...

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Publicado en:Arterioscler Thromb Vasc Biol
Autores principales: Moss, M. Elizabeth, Lu, Qing, Iyer, Surabhi L., Engelbertsen, Daniel, Marzolla, Vincenzo, Caprio, Massimiliano, Lichtman, Andrew H., Jaffe, Iris Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656626/
https://ncbi.nlm.nih.gov/pubmed/31294624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312954
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