Endothelial Mineralocorticoid Receptors Contribute to Vascular Inflammation in Atherosclerosis in a Sex-Specific Manner

OBJECTIVE: Mineralocorticoid receptor (MR) activation is associated with cardiovascular ischemia in humans. This study explores the role of the MR in atherosclerotic mice of both sexes and identifies a sex-specific role for endothelial cell (EC)-MR in vascular inflammation. APPROACH AND RESULTS: In...

Full description

Saved in:
Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Moss, M. Elizabeth, Lu, Qing, Iyer, Surabhi L., Engelbertsen, Daniel, Marzolla, Vincenzo, Caprio, Massimiliano, Lichtman, Andrew H., Jaffe, Iris Z.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656626/
https://ncbi.nlm.nih.gov/pubmed/31294624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312954
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items