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Endothelial Mineralocorticoid Receptors Contribute to Vascular Inflammation in Atherosclerosis in a Sex-Specific Manner

OBJECTIVE: Mineralocorticoid receptor (MR) activation is associated with cardiovascular ischemia in humans. This study explores the role of the MR in atherosclerotic mice of both sexes and identifies a sex-specific role for endothelial cell (EC)-MR in vascular inflammation. APPROACH AND RESULTS: In...

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Dades bibliogràfiques
Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Moss, M. Elizabeth, Lu, Qing, Iyer, Surabhi L., Engelbertsen, Daniel, Marzolla, Vincenzo, Caprio, Massimiliano, Lichtman, Andrew H., Jaffe, Iris Z.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656626/
https://ncbi.nlm.nih.gov/pubmed/31294624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312954
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