No Significant Role for Smooth Muscle Cell Mineralocorticoid Receptors in Atherosclerosis in the Apolipoprotein-E Knockout Mouse Model

Objective: Elevated levels of the hormone aldosterone are associated with increased risk of myocardial infarction and stroke in humans and increased progression and inflammation of atherosclerotic plaques in animal models. Aldosterone acts through the mineralocorticoid receptor (MR) which is express...

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Bibliografiske detaljer
Udgivet i:Front Cardiovasc Med
Main Authors: Moss, M. Elizabeth, DuPont, Jennifer J., Iyer, Surabhi L., McGraw, Adam P., Jaffe, Iris Z.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Cardiovascular Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046374/
https://ncbi.nlm.nih.gov/pubmed/30038907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2018.00081
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