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A novel Ubc9 -dependent pathway regulates SIRT1- ER-α Axis and BRCA1-associated TNBC lung metastasis

Triple negative breast cancer (TNBC) is a heterogeneous disease and has a higher rate of recurrence and distant metastasis. African-American (AA) women have a higher frequency of BRCA1 mutations and TNBC compared to other populations. Basal-like tumors have a higher rate of brain, lung and distant n...

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Библиографические подробности
Опубликовано в: :Integr Mol Med
Главные авторы: Xu, Jingyao, Shumate, Collin, Qin, Yulong, Reddy, Vaishali, Burnam, Yonte, Lopez, Victoria, Okoli, Joel, P Reddy, E Shyam, Rao, Veena N
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6655434/
https://ncbi.nlm.nih.gov/pubmed/31341634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15761/IMM.1000298
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