Ubc9 Mediates Nuclear Localization and Growth Suppression of BRCA1 and BRCA1a Proteins

BRCA1 gene mutations are responsible for hereditary breast and ovarian cancers. In sporadic breast tumors, BRCA1 dysfunction or aberrant subcellular localization is thought to be common. BRCA1 is a nuclear–cytoplasm shuttling protein and the reason for cytoplasmic localization of BRCA1 in young brea...

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Autors principals: QIN, YUNLONG, XU, JINGYAO, AYSOLA, KARTIK, BEGUM, NURJAHAN, REDDY, VAISHALI, CHAI, YULI, GRIZZLE, WILLIAM E., PARTRIDGE, EDWARD E., REDDY, E. SHYAM P., RAO, VEENA N.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329759/
https://ncbi.nlm.nih.gov/pubmed/21344391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22695
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