Insulin Enhances Migration and Invasion in Prostate Cancer Cells by Up-Regulation of FOXC2

Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer (PCa), yet many patients relapse with lethal metastatic disease. With this loss of androgens, increased cell plasticity has been observed as an adaptive response to ADT. This includes gain of invasive and migra...

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Опубликовано в: :Front Endocrinol (Lausanne)
Главные авторы: Sarkar, Phoebe L., Lee, Wendy, Williams, Elizabeth D., Lubik, Amy A., Stylianou, Nataly, Shokoohmand, Ali, Lehman, Melanie L., Hollier, Brett G., Gunter, Jennifer H., Nelson, Colleen C.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Endocrinology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652804/
https://ncbi.nlm.nih.gov/pubmed/31379747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00481
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