Insulin Enhances Migration and Invasion in Prostate Cancer Cells by Up-Regulation of FOXC2

Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer (PCa), yet many patients relapse with lethal metastatic disease. With this loss of androgens, increased cell plasticity has been observed as an adaptive response to ADT. This includes gain of invasive and migra...

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Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Sarkar, Phoebe L., Lee, Wendy, Williams, Elizabeth D., Lubik, Amy A., Stylianou, Nataly, Shokoohmand, Ali, Lehman, Melanie L., Hollier, Brett G., Gunter, Jennifer H., Nelson, Colleen C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652804/
https://ncbi.nlm.nih.gov/pubmed/31379747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00481
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