Androgen-Targeted Therapy-Induced Epithelial Mesenchymal Plasticity and Neuroendocrine Transdifferentiation in Prostate Cancer: An Opportunity for Intervention

Androgens regulate biological pathways to promote proliferation, differentiation, and survival of benign and malignant prostate tissue. Androgen receptor (AR) targeted therapies exploit this dependence and are used in advanced prostate cancer to control disease progression. Contemporary treatment re...

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Vydáno v:Front Oncol
Hlavní autoři: Nouri, Mannan, Ratther, Ellca, Stylianou, Nataly, Nelson, Colleen C., Hollier, Brett G., Williams, Elizabeth D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274903/
https://ncbi.nlm.nih.gov/pubmed/25566507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00370
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