Androgen-Targeted Therapy-Induced Epithelial Mesenchymal Plasticity and Neuroendocrine Transdifferentiation in Prostate Cancer: An Opportunity for Intervention

Androgens regulate biological pathways to promote proliferation, differentiation, and survival of benign and malignant prostate tissue. Androgen receptor (AR) targeted therapies exploit this dependence and are used in advanced prostate cancer to control disease progression. Contemporary treatment re...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Nouri, Mannan, Ratther, Ellca, Stylianou, Nataly, Nelson, Colleen C., Hollier, Brett G., Williams, Elizabeth D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274903/
https://ncbi.nlm.nih.gov/pubmed/25566507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00370
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