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Modeling Pneumonic Plague in Human Precision-Cut Lung Slices Highlights a Role for the Plasminogen Activator Protease in Facilitating Type 3 Secretion

Pneumonic plague is the deadliest form of disease caused by Yersinia pestis. Key to the progression of infection is the activity of the plasminogen activator protease Pla. Deletion of Pla results in a decreased Y. pestis bacterial burden in the lung and failure to progress into the lethal proinflamm...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Banerjee, Srijon K., Huckuntod, Samantha D., Mills, Shalynn D., Kurten, Richard C., Pechous, Roger D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652753/
https://ncbi.nlm.nih.gov/pubmed/31085709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00175-19
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