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Impact of the Pla Protease Substrate α2-Antiplasmin on the Progression of Primary Pneumonic Plague

Many pathogens usurp the host hemostatic system during infection to promote pathogenesis. Yersinia pestis, the causative agent of plague, expresses the plasminogen activator protease Pla, which has been shown in vitro to target and cleave multiple proteins within the fibrinolytic pathway, including...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Eddy, Justin L., Schroeder, Jay A., Zimbler, Daniel L., Bellows, Lauren E., Lathem, Wyndham W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645379/
https://ncbi.nlm.nih.gov/pubmed/26438794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01086-15
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