Systemic upregulation of IL-10 using a non-immunogenic vector reduces growth and rate of dissecting abdominal aortic aneurysm

OBJECTIVE: Recruitment of immunological competent cells to the vessel wall is a crucial step in formation of abdominal aortic aneurysms (AAA). Innate immunity effectors (e.g., macrophages), as well as mediators of adaptive immunity (e.g., T cells), orchestrate a local vascular inflammatory response....

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Adam, Matti, Kooreman, Nigel, Jagger, Ann, Wagenhaeuser, Markus U., Mehrkens, Dennis, Wang, Yongming, Kayama, Yosuke, Toyama, Kensuke, Raaz, Uwe, Schellinger, Isabel N., Maegdefessel, Lars, Spin, Joshua M., Hamming, Jaap F., Quax, Paul H.A., Baldus, Stephan, Wu, Joseph C., Tsao, Philip S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652227/
https://ncbi.nlm.nih.gov/pubmed/29880489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310672
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