Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes

RATIONALE: Accelerated arterial stiffening is a major complication of diabetes with no specific therapy available up to date. OBJECTIVE: The present study investigates the role of the osteogenic transcription factor Runx2 as a potential mediator and therapeutic target of aortic fibrosis and aortic s...

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Publicado no:Circ Res
Main Authors: Raaz, Uwe, Schellinger, Isabel N., Chernogubova, Ekaterina, Warnecke, Christina, Kayama, Yosuke, Penov, Kiril, Hennigs, Jan K., Salomons, Florian, Eken, Suzanne, Emrich, Fabian C., Zheng, Wei H., Adam, Matti, Jagger, Ann, Nakagami, Futoshi, Toh, Ryuji, Toyama, Kensuke, Deng, Alicia, Buerke, Michael, Maegdefessel, Lars, Hasenfuß, Gerd, Spin, Joshua M., Tsao, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553105/
https://ncbi.nlm.nih.gov/pubmed/26208651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.306341
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