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Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes
RATIONALE: Accelerated arterial stiffening is a major complication of diabetes with no specific therapy available up to date. OBJECTIVE: The present study investigates the role of the osteogenic transcription factor Runx2 as a potential mediator and therapeutic target of aortic fibrosis and aortic s...
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| Veröffentlicht in: | Circ Res |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4553105/ https://ncbi.nlm.nih.gov/pubmed/26208651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.306341 |
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