Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development

BACKGROUND: Stiffening of the aortic wall is a phenomenon consistently observed in age and in abdominal aortic aneurysm (AAA). However, its role in AAA pathophysiology is largely undefined. METHODS AND RESULTS: Using an established murine elastase-induced AAA model, we demonstrate that segmental aor...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Raaz, Uwe, Zöllner, Alexander M., Schellinger, Isabel N., Toh, Ryuji, Nakagami, Futoshi, Brandt, Moritz, Emrich, Fabian C., Kayama, Yosuke, Eken, Suzanne, Adam, Matti, Maegdefessel, Lars, Hertel, Thomas, Deng, Alicia, Jagger, Ann, Buerke, Michael, Dalman, Ronald L., Spin, Joshua M., Kuhl, Ellen, Tsao, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439288/
https://ncbi.nlm.nih.gov/pubmed/25904646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.012377
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