Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson’s disease patients

BACKGROUND: Parkinson’s disease (PD) is characterized by the loss of midbrain dopaminergic neurons (DAn). Previously, we described the presence of DNA hyper- and hypo-methylation alterations in induced pluripotent stem cells (iPSC)-derived DAn from PD patients using the Illumina 450K array which pro...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Fernández-Santiago, Rubén, Merkel, Angelika, Castellano, Giancarlo, Heath, Simon, Raya, Ángel, Tolosa, Eduard, Martí, María-José, Consiglio, Antonella, Ezquerra, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651999/
https://ncbi.nlm.nih.gov/pubmed/31337434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0701-6
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