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Comparison of Radiosensitization by HDAC Inhibitors CUDC-101 and SAHA in Pancreatic Cancer Cells

Pancreatic cancer has a poor prognosis. New treatment options are urgently required to improve patient outcomes. One promising new class of anticancer drugs are synthetic histone deacetylase inhibitors (HDACi) which modulate chromatin structure and gene expression by blocking histone deacetylation....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Moertl, Simone, Payer, Sarah, Kell, Rosemarie, Winkler, Klaudia, Anastasov, Natasa, Atkinson, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651299/
https://ncbi.nlm.nih.gov/pubmed/31269745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133259
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