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Antitumor activity of the novel HDAC inhibitor CUDC-101 combined with gemcitabine in pancreatic cancer

Histone deacetylase (HDAC) is overexpressed in multiple cancers including pancreatic cancer (PC). However, the effects of histone deacetylase inhibitor (HDACi) on apoptosis and epithelial-mesenchymal transition (EMT) differ in various cancers. In this study, we aimed to investigate the anti-tumor ef...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Ji, Meiying, Li, Zhenling, Lin, Zhenhua, Chen, Liyan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325471/
https://ncbi.nlm.nih.gov/pubmed/30662800
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