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Comparison of Radiosensitization by HDAC Inhibitors CUDC-101 and SAHA in Pancreatic Cancer Cells

Pancreatic cancer has a poor prognosis. New treatment options are urgently required to improve patient outcomes. One promising new class of anticancer drugs are synthetic histone deacetylase inhibitors (HDACi) which modulate chromatin structure and gene expression by blocking histone deacetylation....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Moertl, Simone, Payer, Sarah, Kell, Rosemarie, Winkler, Klaudia, Anastasov, Natasa, Atkinson, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651299/
https://ncbi.nlm.nih.gov/pubmed/31269745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133259
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