Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

Introduction: Lipid mediators (LMs) comprise bioactive metabolites of polyunsaturated fatty acids, including pro-inflammatory prostaglandins (PGs), thromboxanes (TXs), and leukotrienes (LTs), as well as specialized pro-resolving mediators (SPMs). They are essentially biosynthesized via cyclooxygenas...

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Publicat a:Front Pharmacol
Autors principals: Gerstmeier, Jana, Seegers, Julia, Witt, Finja, Waltenberger, Birgit, Temml, Veronika, Rollinger, Judith M., Stuppner, Hermann, Koeberle, Andreas, Schuster, Daniela, Werz, Oliver
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650749/
https://ncbi.nlm.nih.gov/pubmed/31379572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00797
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