Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

Hip geometry is an important predictor of fracture. We performed a meta-analysis of GWAS studies in adults to identify genetic variants that are associated with proximal femur geometry phenotypes. We analyzed four phenotypes: (i) femoral neck length; (ii) neck-shaft angle; (iii) femoral neck width,...

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I publikationen:J Bone Miner Res
Huvudupphovsmän: Hsu, Yi-Hsiang, Estrada, Karol, Evangelou, Evangelos, Ackert-Bicknell, Cheryl, Akesson, Kristina, Beck, Thomas, Brown, Suzanne J, Capellini, Terence, Carbone, Laura, Cauley, Jane, Cheung, Ching-Lung, Cummings, Steven R, Czerwinski, Stefan, Demissie, Serkalem, Econs, Michael, Evans, Daniel, Farber, Charles, Gautvik, Kaare, Harris, Tamara, Kammerer, Candace, Kemp, John, Koller, Daniel L, Kung, Annie, Lawlor, Debbie, Lee, Miryoung, Lorentzon, Mattias, McGuigan, Fiona, Medina-Gomez, Carolina, Mitchell, Braxton, Newman, Anne, Nielson, Carrie, Ohlsson, Claes, Peacock, Munro, Reppe, Sjur, Richards, J Brent, Robbins, John, Sigurdsson, Gunnar, Spector, Timothy D, Stefansson, Kari, Streeten, Elizabeth, Styrkarsdottir, Unnur, Tobias, Jonathan, Trajanoska, Katerina, Uitterlinden, André, Vandenput, Liesbeth, Wilson, Scott G, Yerges-Armstrong, Laura, Young, Mariel, Zillikens, Carola, Rivadeneira, Fernando, Kiel, Douglas P, Karasik, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650334/
https://ncbi.nlm.nih.gov/pubmed/30888730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3698
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